<AN 04M10B04-03E-A> <02/26/2007>
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High Shear Fluid Processor with MW100 and DXP
Industry: Pharmaceutical/Biotechnology
Product: Network Solutions
MW100 and DXP
Introduction
A leading manufacturer of high shear fluid pro cessors
was looking for a sol ution to provide secure, stable
pressure readings. The speed of the process typically
demands a very fast data-logger with enough
intelligence to filter out noise while providing accurate
results. High-speed sample rates and math logic in
MW100 combined with se cure, validated logging in the
DXP deliver stable, consistent results from an
otherwise noisy process.
Application
A simplified explanation of a high shear fluid pro cessor
is as follows: highly pressurized fluids are pumped
through a tight orifice or restriction – the resultin g
pressure change from maximum pre ssure at the
center of the restriction to minimum pressure o n the far
side of the orifice causes cells an d other particles to be
disrupted and sheared.
A key process variable in this application is pressure.
Due to the nature of pumps turning on and off, noise is
always present in the pressure signal as pumps
engage. Many measureme nt and recording systems
lack both speed and intelligence to accurately capture
changes in pressure caused by these pumps. As a
result, they are unable to filter out resultant noise.
Customers require solutions that record and display
accurate pressure readings while eliminating spi ke s
associated with pumping. Since many of these high
shear fluid proces sors are destined for major
biotechnology and pharmaceutical custo mers,
recorded data must also adhere to 21 CFR Part 11
requirements and be valid ation friendly.
Solution
An ideal solution for recordi ng and displaying data on
high shear fluid processors is a combination of both
the MW100 and the DXP. Yokogawa’s video ba sed
DXP recorder is pharmaceutical and bio tech friendly.
This instrument has be en specifically designed for
easy validation in the most demanding environm ents.
DXP has multiple levels of security incl uding secure
logins and true encrypted data files. DXP’s
configuration file is an integral part of the histori cal
data file thereby guaranteeing the validity of the
recording. MW100 is Yokogawa’s latest data
acquisition system that features fast sam pling rates,
superior logic capabilities and multiple communication
options.
The DXP and the MW100 were networked using built -
in Modbus communication s. The MW100 functions as
an intelligent data collector and the DXP as the official
data-repository where final information i s re corded and
displayed. The MW100 takes advantag e of its 100 ms
sampling rate (it can sample as fast as 10 ms) plus on
board math logic. Custom computations were created
within the MW100 to take raw pre ssure signals wired
as analog inputs and filter the rea dings. Pump noise is
ignored and only stable pressure sign als are
transmitted to the DXP, which both records and
displays clean, stable pressures.
This customer is extremely pleased that they were
able to tame the noisy process while providing a high
quality, reliable next generation high shear fluid
processor.
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